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pentobarbital will lessen the extent or outcome of methadone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will lower the level or impact of alfuzosin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.

pentobarbital will minimize the level or influence of darifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

pentobarbital will decrease the level or influence of itraconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.

pentobarbital will lower the level or outcome of buprenorphine buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

lasmiditan, pentobarbital. Possibly raises outcomes of the other by sedation. Use Warning/Monitor. Coadministration of lasmiditan together with other CNS depressant medicines, which includes Liquor have not been evaluated in medical experiments. Lasmiditan may possibly cause sedation, together with other cognitive and/or neuropsychiatric adverse reactions.

pentobarbital will lessen the level or influence of temsirolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital will lower the extent or effect of vinorelbine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.

Medicine that involve prior authorization. This restriction requires that specific medical requirements be met prior get more info to the acceptance of the prescription.

pentobarbital will minimize the extent or effect of parecoxib by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Check.

pentobarbital will minimize the extent or effect of estradiol vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

fentanyl iontophoretic transdermal process and pentobarbital both of those increase sedation. Stay away from or Use Alternate Drug. Limit use to patients for whom option treatment method alternatives are insufficient

pentobarbital will decrease the level or effect of pimavanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Keep away from coadministration if possible. Keep an eye on for minimized pimavanserin efficacy. A rise in pimavanserin dosage can be desired.

Comment: Barbiturates might enhance adverse results, together with respiratory despair, produced by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates boost metabolism and reduce blood concentrations of TCAs.