pentobarbital will lessen the extent or outcome of methadone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital will lower the level or impact of alfuzosin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.pentobarbital will minimize the level or influence of darifenacin b… Read More